Original Article. A Comparison of Enalapril with Hydralazine Isosorbide Dinitrate in the Treatment of Chronic Congestive Heart Failure. Jay N. Cohn, M.D., Gary .Background We examined whether a fixed dose of both isosorbide dinitrate and hydralazine provides additional benefit in blacks with advanced heart failure, a subgroup .Cole RT, Kalogeropoulos AP, Georgiopoulou VV, et al. Hydralazine and isosorbide dinitrate in heart failure historical perspective, mechanisms, and future directions… NAME . Substance Hydralazine Hydralazine Hydrochloride . Group Vasodilator Antihypertensive . Synonyms Hydralazine Hydrochloride Hydrazinophatalazine .Hydralazine is a phthalazine derivative with antihypertensive effects. Hydralazine exerts its vasodilatory effects through modification of the contractile state of .
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Original Article from The New England Journal of Medicine A Comparison of Enalapril with Hydralazine Isosorbide Dinitrate in the Treatment of Chronic Congestive Heart Failure..A comparison of enalapril with hydralazine isosorbide dinitrate in the treatment of chronic congestive heart failure. The latter regimen was identical to that used with a similar patient population in the effective treatment arm of our previous Vasodilator Heart Failure Trial..
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